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Day

July 25, 2024
Original Investigation

Bintrafusp Alfa for Recurrent or Metastatic Cervical Cancer After Platinum Failure: A Nonrandomized Controlled Trial

Abstract Full Text
open access
С槼ºÖ±²¥ Oncol. Published online July 25, 2024. doi:10.1001/jamaoncol.2024.2145

This phase 2 nonrandomized controlled trial evaluates the safety and response rates of bintrafusp alfa in patients with recurrent or metastatic cervical cancer.

Bilateral Mastectomy and Breast Cancer Mortality

Abstract Full Text
С槼ºÖ±²¥ Oncol. Published online July 25, 2024. doi:10.1001/jamaoncol.2024.2212

This cohort study estimates the 20-year cumulative risk of breast cancer mortality among women with stage 0 to III unilateral breast cancer according to the type of initial surgery performed.

Atezolizumab Before and After Chemoradiation for Unresectable Stage III Non–Small Cell Lung Cancer: A Phase II Nonrandomized Controlled Trial

Abstract Full Text
С槼ºÖ±²¥ Oncol. Published online July 25, 2024. doi:10.1001/jamaoncol.2024.1897

This nonrandomized controlled trial evaluates the clinical outcomes of atezolizumab treatment before and after chemoradiation therapy for unresectable stage III non–small cell lung cancer (NSCLC).

Brief Report

B-Cell Maturation Antigen/CD19 Dual-Targeting Immunotherapy in Newly Diagnosed Multiple Myeloma

Abstract Full Text
open access
С槼ºÖ±²¥ Oncol. Published online July 25, 2024. doi:10.1001/jamaoncol.2024.2172

This single-arm, open-label phase 1 cohort study examines the safety, patient health, and survival outcomes of GC012F in individuals with high-risk newly diagnosed multiple myeloma.

Research Letter

Population-Based Incidence of Cervical Intraepithelial Neoplasia Across 14 Years of HPV Vaccination

Abstract Full Text
С槼ºÖ±²¥ Oncol. Published online July 25, 2024. doi:10.1001/jamaoncol.2024.2673

This cohort study examines the incidence of cervical intraepithelial neoplasia during a period of increasing human papillomavirus (HPV) vaccination coverage from 2007 to 2020.

Review

BRCA1, BRCA2, and Associated Cancer Risks and Management for Male Patients: A Review

Abstract Full Text
has active quiz
С槼ºÖ±²¥ Oncol. Published online July 25, 2024. doi:10.1001/jamaoncol.2024.2185

This narrative review describes the identification of male BRCA1/2 pathogenic variant carriers, associated cancer risks, and management recommendations.

Viewpoint

Hormone Deprivation–Free Survival—Inequities Persist in Research Priorities for Patients With Cancer

Abstract Full Text
С槼ºÖ±²¥ Oncol. Published online July 25, 2024. doi:10.1001/jamaoncol.2024.2142

This Viewpoint discusses the importance of hormone deprivation–free survival as an end point for both men with prostate cancer and women with breast cancer.

Editorial

Contralateral Breast Cancer Remains a Complex Biologic Conundrum

Abstract Full Text
С槼ºÖ±²¥ Oncol. Published online July 25, 2024. doi:10.1001/jamaoncol.2024.2205
Editor's Note

Immunotherapy Before Chemoradiotherapy—More Is Better?

Abstract Full Text
С槼ºÖ±²¥ Oncol. Published online July 25, 2024. doi:10.1001/jamaoncol.2024.0993
Poetry and Oncology

Cara

Abstract Full Text
С槼ºÖ±²¥ Oncol. Published online July 25, 2024. doi:10.1001/jamaoncol.2024.2188
July 18, 2024
Original Investigation

Neoadjuvant Exercise Therapy in Prostate Cancer: A Phase 1, Decentralized Nonrandomized ControlledTrial

Abstract Full Text
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С槼ºÖ±²¥ Oncol. Published online July 18, 2024. doi:10.1001/jamaoncol.2024.2156

This nonrandomized clinical trial examines 6 escalated exercise therapy dose levels ranging from 90 to 450 minutes per week for men with treatment-naive localized prostate cancer.

Brief Report

Immunotherapy vs Best Supportive Care for Patients With Hepatocellular Cancer With Child-Pugh B Dysfunction

Abstract Full Text
С槼ºÖ±²¥ Oncol. Published online July 18, 2024. doi:10.1001/jamaoncol.2024.2166

This case series examines the association of immune checkpoint inhibitor–based therapies vs best supportive care with the overall survival of patients with unresectable hepatocellular carcinoma and Child-Pugh class B liver dysfunction.

Viewpoint

Advancing Genomic Cancer Medicine in Rural and Underserved States

Abstract Full Text
С槼ºÖ±²¥ Oncol. Published online July 18, 2024. doi:10.1001/jamaoncol.2024.1926

This Viewpoint presents an organizational and social template for medical communities to provide contemporary care for patients with cancer in rural and underserved states.

Editorial

Exercise for Prostate Cancer—Worthy Goals but Suboptimal Trial Designs

Abstract Full Text
С槼ºÖ±²¥ Oncol. Published online July 18, 2024. doi:10.1001/jamaoncol.2024.2057
July 11, 2024
Original Investigation

Waterpipe Tobacco Smoking and Risk of Cancer Mortality

Abstract Full Text
С槼ºÖ±²¥ Oncol. Published online July 11, 2024. doi:10.1001/jamaoncol.2024.1939

This cohort study evaluates the association between waterpipe tobacco smoking and the risk of cancer mortality in Vietnam.

Response-Adapted Ultralow-Dose Radiation Therapy for Orbital Indolent B-Cell Lymphoma: A Phase 2 Nonrandomized Controlled Trial

Abstract Full Text
С槼ºÖ±²¥ Oncol. Published online July 11, 2024. doi:10.1001/jamaoncol.2024.2112

This nonrandomized controlled trial aims to determine if a response-adapted radiation therapy strategy will result in excellent disease outcomes while reducing orbital morbidity.

Measurable Residual Disease and Clinical Outcomes in Chronic Lymphocytic Leukemia: A Systematic Review and Meta-Analysis

Abstract Full Text
С槼ºÖ±²¥ Oncol. Published online July 11, 2024. doi:10.1001/jamaoncol.2024.2122

This systematic review and meta-analysis assesses the association between measurable residual disease and progression-free survival in chronic lymphocytic leukemia treated with targeted agents.

Special Communication

Initial Management of BRAF V600E-Variant Anaplastic Thyroid Cancer: The FAST Multidisciplinary Group Consensus Statement

Abstract Full Text
has active quiz
С槼ºÖ±²¥ Oncol. Published online July 11, 2024. doi:10.1001/jamaoncol.2024.2133

This Consensus Statement summarizes new evidence-based recommendations and reaffirms standards for timely initial management of BRAF V600E-variant anaplastic thyroid cancer.

Viewpoint

Postoperative Management of Prostate Cancer—Optimizing Prostate Cancer Care

Abstract Full Text
С槼ºÖ±²¥ Oncol. Published online July 11, 2024. doi:10.1001/jamaoncol.2024.1887

This Viewpoint discusses the end point analyses and results of the RACICALS-RT study.

Comment & Response

Chemotherapy, Radiation Therapy, and Nasopharyngeal Carcinoma

Abstract Full Text
С槼ºÖ±²¥ Oncol. Published online July 11, 2024. doi:10.1001/jamaoncol.2024.2519

Chemotherapy, Radiation Therapy, and Nasopharyngeal Carcinoma

Abstract Full Text
С槼ºÖ±²¥ Oncol. Published online July 11, 2024. doi:10.1001/jamaoncol.2024.2522

Chemotherapy, Radiation Therapy, and Nasopharyngeal Carcinoma—Reply

Abstract Full Text
С槼ºÖ±²¥ Oncol. Published online July 11, 2024. doi:10.1001/jamaoncol.2024.2525
Correction

Errors in Table

Abstract Full Text
free access
С槼ºÖ±²¥ Oncol. Published online July 11, 2024. doi:10.1001/jamaoncol.2024.3130

Error in Byline

Abstract Full Text
free access
С槼ºÖ±²¥ Oncol. Published online July 11, 2024. doi:10.1001/jamaoncol.2024.3182
July 3, 2024
Original Investigation

Pancreatic Cancer Surveillance and Survival of High-Risk Individuals

Abstract Full Text
open access
С槼ºÖ±²¥ Oncol. Published online July 3, 2024. doi:10.1001/jamaoncol.2024.1930

This cohort study compares survival of high-risk patients with screen-detected pancreatic cancer with a matched cohort from the Surveillance, Epidemiology, and End Results program.

Brief Report

Adjuvant Gemcitabine Plus Cisplatin and Chemoradiation in Patients With Gallbladder Cancer: A Randomized Clinical Trial

Abstract Full Text
С槼ºÖ±²¥ Oncol. Published online July 3, 2024. doi:10.1001/jamaoncol.2024.1944

This randomized clinical trial examines adequate early survival rates of treatment with adjuvant gemcitabine plus cisplatin compared with concurrent chemoradiation with capecitabine in patients with resected stage II and stage III gallbladder cancers.

Cancer Care Chronicles

Caregiver Burden—Within and Without

Abstract Full Text
С槼ºÖ±²¥ Oncol. Published online July 3, 2024. doi:10.1001/jamaoncol.2024.2482

This essay describes the experience of an oncologist in India and palliative care involving grieving families and coconuts.

Comment & Response

More Benefits of Tai Chi Than Aerobic Exercise in Patients With Advanced Lung Cancer

Abstract Full Text
С槼ºÖ±²¥ Oncol. Published online July 3, 2024. doi:10.1001/jamaoncol.2024.2453

More Benefits of Tai Chi Than Aerobic Exercise in Patients With Advanced Lung Cancer—Reply

Abstract Full Text
С槼ºÖ±²¥ Oncol. Published online July 3, 2024. doi:10.1001/jamaoncol.2024.2456
July 1, 2024
Original Investigation

Fluorine-18 Prostate-Specific Membrane Antigen–1007 PET/CT vs Multiparametric MRI for Locoregional Staging of Prostate Cancer

Abstract Full Text
open access
С槼ºÖ±²¥ Oncol. Published online July 1, 2024. doi:10.1001/jamaoncol.2024.3196

This study assesses the accuracy of fluorine-18 prostate-specific membrane antigen–1007 positron emission tomography (PET)/computed tomography (CT) compared to multiparametric magnetic resonance imaging (MRI) in locoregional staging of prostate cancer.

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